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KMID : 0383820080650040323
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Tuberculosis and Respiratory Diseases
2008 Volume.65 No. 4 p.323 ~ p.327
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Systemic Lupus Erythematosus Associated with Interstitial Pneumonia and Achalasia
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Kwon Hye-Lee
Hong Kyung-Wook
Lim Seung-Jin
Park So-Young
Bae Young-Deok
Kim Kyoung-Ho
Choi Jeong-Hee
Mo Eun-Kyung
Park Yong-Bum
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Abstract
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Systemic lupus erythematosus (SLE) is a multisystem disorder where the etiology is not clearly known. Symptomatic
chronic interstitial pneumonitis is an uncommon manifestation, with a reported prevalence of 3∼13%. Achalasia is rare disease that presents with failure in the relaxation of the esophagus sphincter. A 22-year-old woman was admitted to our hospital because of fever, cough and dyspnea. The patient had a history of pericardial effusion and Raynaud’s phenomenon. The results of laboratory tests indicated the presence of lymphopenia and included positive antibody tests for antinuclear antibody and anti Sm antibody. A chest X-ray demonstrated the presence of peribronchial infiltration on both lung fields. A Chest CT image showed interlobar septal thickening, ground-glass opacity and a honeycomb appearance in both lung fields and esophageal dilatation with air fluid level. An esophagogram showed the presence of dilated esophagus ends that represented the non-relaxed lower esophageal sphincter. Manometry demonstrated incomplete sphincter relaxation. The case was diagnosed as systemic lupus erythematosus associated with interstitial pneumonia and achalasia.
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KEYWORD
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Interstitial pneumonia, Achalasia, SLE
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